\( % groupings of objects. \newcommand{\set}[1]{\left\{ #1 \right\}} \newcommand{\seq}[1]{\left(#1\right)} \newcommand{\ang}[1]{\langle#1\rangle} \newcommand{\tuple}[1]{\left(#1\right)} \newcommand{\size}[1]{\left| #1\right|} \newcommand{\comp}{\circ} % numerical shortcuts. \newcommand{\abs}[1]{\left| #1\right|} \newcommand{\floor}[1]{\left\lfloor #1 \right\rfloor} \newcommand{\ceil}[1]{\left\lceil #1 \right\rceil} % linear algebra shortcuts. \newcommand{\change}{\Delta} \newcommand{\norm}[1]{\left\| #1\right\|} \newcommand{\dprod}[1]{\langle#1\rangle} \newcommand{\linspan}[1]{\langle#1\rangle} \newcommand{\conj}[1]{\overline{#1}} \newcommand{\der}[1]{\frac{d#1}{dx}} \newcommand{\lap}{\Delta} \newcommand{\kron}{\otimes} \newcommand{\nperp}{\nvdash} \newcommand{\mat}[1]{\left[ \begin{smallmatrix}#1 \end{smallmatrix} \right]} % derivatives and limits \newcommand{\partder}[2]{\frac{\partial #1}{\partial #2}} \newcommand{\partdern}[3]{\frac{\partial^{#3 #1}}{\partial #2^{#3}}} \newcommand{\gradient}{\nabla} \newcommand{\subdifferential}{\partial} % Arrows \newcommand{\diverge}{\nearrow} \newcommand{\notto}{\nrightarrow} \newcommand{\up}{\uparrow} \newcommand{\down}{\downarrow} % gets and gives are defined! % ordering operators \newcommand{\oleq}{\preceq} \newcommand{\ogeq}{\succeq} % programming and logic operators \newcommand{\dfn}{:=} \newcommand{\assign}{:=} \newcommand{\co}{\ co\ } \newcommand{\en}{\ en\ } % logic operators \newcommand{\xor}{\oplus} \newcommand{\Land}{\bigwedge} \newcommand{\Lor}{\bigvee} \newcommand{\finish}{\Box} \newcommand{\contra}{\Rightarrow \Leftarrow} \newcommand{\iseq}{\stackrel{_?{=}}} % Set theory \newcommand{\symdiff}{\Delta} \newcommand{\setdiff}{\backslash} \newcommand{\union}{\cup} \newcommand{\inters}{\cap} \newcommand{\Union}{\bigcup} \newcommand{\Inters}{\bigcap} \newcommand{\nullSet}{\phi} % graph theory \newcommand{\nbd}{\Gamma} % Script alphabets % For reals, use \Re % greek letters \newcommand{\eps}{\epsilon} \newcommand{\del}{\delta} \newcommand{\ga}{\alpha} \newcommand{\gb}{\beta} \newcommand{\gd}{\del} \newcommand{\gp}{\pi} \newcommand{\gf}{\phi} \newcommand{\gh}{\eta} \newcommand{\gF}{\Phi} \newcommand{\gl}{\lambda} \newcommand{\gm}{\mu} \newcommand{\gn}{\nu} \newcommand{\gr}{\rho} \newcommand{\gs}{\sigma} \newcommand{\gth}{\theta} \newcommand{\gx}{\xi} \newcommand{\gw}{\omega} \newcommand{\sw}{\sigma} \newcommand{\SW}{\Sigma} \newcommand{\ew}{\lambda} \newcommand{\EW}{\Lambda} \newcommand{\Del}{\Delta} \newcommand{\gD}{\Delta} \newcommand{\gG}{\Gamma} \newcommand{\gW}{\Omega} \newcommand{\gS}{\Sigma} \newcommand{\gTh}{\Theta} % Bold english letters. \newcommand{\bA}{\mathbf{A}} \newcommand{\bB}{\mathbf{B}} \newcommand{\bC}{\mathbf{C}} \newcommand{\bD}{\mathbf{D}} \newcommand{\bE}{\mathbf{E}} \newcommand{\bF}{\mathbf{F}} \newcommand{\bG}{\mathbf{G}} \newcommand{\bH}{\mathbf{H}} \newcommand{\bI}{\mathbf{I}} \newcommand{\bJ}{\mathbf{J}} \newcommand{\bK}{\mathbf{K}} \newcommand{\bL}{\mathbf{L}} \newcommand{\bM}{\mathbf{M}} \newcommand{\bN}{\mathbf{N}} \newcommand{\bO}{\mathbf{O}} \newcommand{\bP}{\mathbf{P}} \newcommand{\bQ}{\mathbf{Q}} \newcommand{\bR}{\mathbf{R}} \newcommand{\bS}{\mathbf{S}} \newcommand{\bT}{\mathbf{T}} \newcommand{\bU}{\mathbf{U}} \newcommand{\bV}{\mathbf{V}} \newcommand{\bW}{\mathbf{W}} \newcommand{\bX}{\mathbf{X}} \newcommand{\bY}{\mathbf{Y}} \newcommand{\bZ}{\mathbf{Z}} \newcommand{\bba}{\mathbf{a}} \newcommand{\bbb}{\mathbf{b}} \newcommand{\bbc}{\mathbf{c}} \newcommand{\bbd}{\mathbf{d}} \newcommand{\bbe}{\mathbf{e}} \newcommand{\bbf}{\mathbf{f}} \newcommand{\bbg}{\mathbf{g}} \newcommand{\bbh}{\mathbf{h}} \newcommand{\bbk}{\mathbf{k}} \newcommand{\bbl}{\mathbf{l}} \newcommand{\bbm}{\mathbf{m}} \newcommand{\bbn}{\mathbf{n}} \newcommand{\bbp}{\mathbf{p}} \newcommand{\bbq}{\mathbf{q}} \newcommand{\bbr}{\mathbf{r}} \newcommand{\bbs}{\mathbf{s}} \newcommand{\bbt}{\mathbf{t}} \newcommand{\bbu}{\mathbf{u}} \newcommand{\bbv}{\mathbf{v}} \newcommand{\bbw}{\mathbf{w}} \newcommand{\bbx}{\mathbf{x}} \newcommand{\bby}{\mathbf{y}} \newcommand{\bbz}{\mathbf{z}} \newcommand{\0}{\mathbf{0}} \newcommand{\1}{\mathbf{1}} % Caligraphic english alphabet \newcommand{\cA}{\mathcal{A}} \newcommand{\cB}{\mathcal{B}} \newcommand{\cC}{\mathcal{C}} \newcommand{\cD}{\mathcal{D}} \newcommand{\cE}{\mathcal{E}} \newcommand{\cF}{\mathcal{F}} \newcommand{\cG}{\mathcal{G}} \newcommand{\cH}{\mathcal{H}} \newcommand{\cI}{\mathcal{I}} \newcommand{\cJ}{\mathcal{J}} \newcommand{\cK}{\mathcal{K}} \newcommand{\cL}{\mathcal{L}} \newcommand{\cM}{\mathcal{M}} \newcommand{\cN}{\mathcal{N}} \newcommand{\cO}{\mathcal{O}} \newcommand{\cP}{\mathcal{P}} \newcommand{\cQ}{\mathcal{Q}} \newcommand{\cR}{\mathcal{R}} \newcommand{\cS}{\mathcal{S}} \newcommand{\cT}{\mathcal{T}} \newcommand{\cU}{\mathcal{U}} \newcommand{\cV}{\mathcal{V}} \newcommand{\cW}{\mathcal{W}} \newcommand{\cX}{\mathcal{X}} \newcommand{\cY}{\mathcal{Y}} \newcommand{\cZ}{\mathcal{Z}} % Formatting shortcuts \newcommand{\red}[1]{\textcolor{red}{#1}} \newcommand{\blue}[1]{\textcolor{blue}{#1}} \newcommand{\htext}[2]{\texorpdfstring{#1}{#2}} % Statistics \newcommand{\distr}{\sim} \newcommand{\stddev}{\sigma} \newcommand{\covmatrix}{\Sigma} \newcommand{\mean}{\mu} \newcommand{\param}{\theta} \newcommand{\gthEst}{\hat{\theta}} \newcommand{\ftr}{\phi} \newcommand{\est}[1]{\hat{#1}} % General utility \newcommand{\todo}[1]{\textbf{[TODO]}] \footnote{TODO: #1}} \newcommand{\tbc}{[\textbf{Incomplete}]} \newcommand{\chk}{[\textbf{Check}]} \newcommand{\why}{[\textbf{Find proof}]} \newcommand{\opt}[1]{\textit{#1}} \newcommand{\experience}[1]{[\textbf{Personal Experience}]: #1 \blacktriangle} \newcommand{\pf}[1]{[\textbf{Proof}]: #1 \Box} \newcommand{\core}[1]{\textbf{Core Idea}: #1 \Arrowvert} \newcommand{\example}[1]{\textbf{Example}: #1 \blacktriangle} \newcommand{\error}[1]{\textbf{Error alert}: #1 \triangle} \newcommand{\oprob}{[\textbf{OP}]: } \renewcommand{\~}{\htext{$\sim$}{~}} \DeclareMathOperator*{\argmin}{arg\,min} \DeclareMathOperator*{\argmax}{arg\,max} \)

+Genetic Engineering

Recombinant DNA technology

This is a cumbersome method of modification whereby gene fragments from one organism are inserted into vectors such as bacterial plasmids or viruses, which can then transfer them into the organism of interest. Though this technology had early successes in the 1970’s, its application was constrained due to limitations in scope and scale.

With CRISPR-Cas9

CRISPR/Cas9 edits genes by precisely cutting DNA and then letting natural DNA repair processes to take over. The system consists of two parts: the Cas9 enzyme and a guide RNA.

+Genetic Engineering
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